Pleuropulmonary blastomas (PPBs) forms in tissues of the lung and pleura (the tissue that covers the lungs and lines the chest). PPBs can create organs including the lungs, heart, aorta and pulmonary artery, or diaphragm (the main breathing muscle under the lungs).
PPB are three types:
- Type I tumors are cyst-like tumor in the lung. They are most common in children 2 years of age and usually can be treated. Type of IR tumors that have not spread or tumor is large or small.
- Type II cyst-like tumor with some solid parts. Sometimes the tumor has spread to the brain.
- Type III tumors are solid tumors. These tumors often spread to the brain.
Risk factors, signs and symptoms, and troubleshooting and staging test
PPB has increased following risk:
- Having pleuropulmonary blastoma cancer family syndrome.
- DICER1 is a change in the gene.
Upcoming may cause symptoms and lung symptoms were Gus PPB. Check with your child’s doctor if your child has any of the following:
- A cough that does not go away.
- Trouble breathing.
- Lung infections, such as pneumonia.
- Pain in the chest or abdomen.
- Loss of appetite.
- Weight loss for no known reason.
- Feeling very tired.
There are other conditions that can cause PPB is the same signs and symptoms.
PPB can be diagnosed and staged Test matches are as follows:
- Physical exam and history.
- Chest X-ray.
- CT scans.
- PET scan.
See general information section for a description of these tests and procedures.
PPB used to diagnose other tests include the following:
- Bronchoscopy: A procedure to look inside the trachea and large airways in the lung for abnormal areas. A bronchoscope is inserted through the nose or mouth and trachea into the lungs. A bronchoscope is a thin, tube-like instrument with a light and a lens for viewing. It also examined tissue samples under a microscope for signs of cancer which can be a tool to remove.
- Thoracoscopy: A surgical procedure to look at the organs inside the chest to check for abnormal areas. The anksyun (cut) the substance btuyn tuu Rabbis, and the thurakuskupy ansyrtd antu were active. A thoracoscope is a thin, tube-like instrument with a light and a lens for viewing. It also examined under a microscope for signs of tissue or lymph node samples, which can be a tool to remove the cancer. In some cases, the esophagus or the procedure used to remove part of the lung. thoracoscope is certain tissues, organs, or lymph nodes can not be reached, a thoracotomy may be done. In this process, a large incision is made between the ribs and the chest is opened.
The PPBs spread or recur (come back), maybe even after being removed by surgery.
The prognosis (chance of recovery) depends on the following:
- pleuropulmonary blastoma type.
- Whether the tumor has spread to other parts of the body diagnosis.
- Whether the tumor has been completely removed by surgery.
Children are treated following the pleuropulmonary blastoma:
- Surgery to remove the entire lobe is in, with or without chemotherapy for lung tumors.
- Clinical trial of targeted therapy using a monoclonal antibody targeting.